[HTML][HTML] Expression profiling of human donor lungs to understand primary graft dysfunction after lung transplantation
M Ray, S Dharmarajan, J Freudenberg… - American Journal of …, 2007 - Elsevier
Lung transplantation is the treatment of choice for end‐stage pulmonary diseases. A limited
donor supply has resulted in 4000 patients on the waiting list. Currently, 10–20% of donor
organs offered for transplantation are deemed suitable under the selection criteria, of which
15–25% fail due to primary graft dysfunction (PGD). This has spawned efforts to re‐examine
the current selection criteria as well as search for alternative donor lungs selection criteria. In
this study, we attempt to further our understanding of PGD by observing the changes in gene …
donor supply has resulted in 4000 patients on the waiting list. Currently, 10–20% of donor
organs offered for transplantation are deemed suitable under the selection criteria, of which
15–25% fail due to primary graft dysfunction (PGD). This has spawned efforts to re‐examine
the current selection criteria as well as search for alternative donor lungs selection criteria. In
this study, we attempt to further our understanding of PGD by observing the changes in gene …
